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Diabetic Muscle Atrophy: Causes, Symptoms, Treatment, and the Importance of Blood Glucose Monitoring

Diabetic Muscle Atrophy: Causes, Symptoms, Treatment, and the Importance of Blood Glucose Monitoring

Diabetes is one of the most common chronic conditions worldwide, affecting hundreds of millions of people. Most are familiar with the well-known complications—such as heart disease, stroke, vision loss, kidney failure, and the risk of lower-limb amputation. Yet there is one lesser-known complication that can seriously affect quality of life: diabetic muscle atrophy.
What makes this complication particularly unique is that it affects only about 1% of adults with diabetes, and its underlying mechanism differs from other types of diabetic nerve damage. Early recognition of symptoms, understanding the causes, and regularly monitoring blood glucose levels with a blood glucose meter or testing device are essential steps to reduce its progression.

1. What is Diabetic Muscle Atrophy?


Teo cơ do đái tháo đường là gì
 

Diabetic muscle atrophy, also referred to by its medical terms:

  • Proximal neuropathy
  • Diabetic lumbosacral radiculoplexus neuropathy
  • Bruns-Garland syndrome

Unlike typical peripheral neuropathy, which primarily affects the feet and lower legs, diabetic muscle atrophy mainly damages nerves in the thighs, hips, and buttocks, and may sometimes spread to the chest or abdomen. It usually begins suddenly or subacutely, often on one side of the body, before gradually spreading to both sides.

2. The Importance of Monitoring Blood Glucose

The root cause of nearly all diabetic complications, including muscle atrophy, is prolonged hyperglycemia or rapid fluctuations in blood sugar levels. This makes regular glucose monitoring a key preventive measure.
Modern blood glucose meters allow patients to test easily at home, enabling early detection of abnormalities and timely adjustments in diet, exercise, and medication. This not only prevents vascular complications but also reduces the risk of rare nerve conditions such as muscle atrophy.

3. Symptoms of Diabetic Muscle Atrophy


Triệu chứng của teo cơ do đái tháo đường
 

This condition typically occurs in older adults (average age around 65), though younger individuals are not exempt. Common symptoms include:

  • Severe nerve pain in the thighs, hips, or buttocks, often starting on one side
  • Noticeable muscle weakness, especially in proximal muscles
  • Muscle wasting in the affected area
  • Rapid, unexplained weight loss despite normal eating
  • Tingling or numbness
  • Loss of tendon reflexes
  • Foot drop
  • Autonomic symptoms: sweating changes, constipation, or diarrhea
  • Orthostatic hypotension (dizziness upon standing)

The condition can last from several months to up to two years, then stabilize with partial recovery. However, without good blood glucose control, recurrence and long-term muscle weakness are common.

4. Causes and Risk Factors

The exact mechanism remains unclear, though immune-mediated microvascular inflammation is believed to play a role.
Higher risk is seen in:

  • Individuals over 50
  • Type 2 diabetes patients
  • Those with rapid or overly strict blood sugar control
  • People with low body mass index (BMI)

Potential triggers include:

  • Starting diabetes treatment
  • Recent vaccination
  • Physical trauma
  • Infections

5. Possible Complications


Biến chứng có thể gặp
 

Without timely management, diabetic muscle atrophy may lead to:

  • Paralysis of both legs or even all four limbs
  • Severe mobility impairment
  • Depression or anxiety disorders
  • Unnecessary spinal surgeries due to misdiagnosis

This highlights the importance of regular home glucose testing and health checkups to catch early warning signs and avoid unnecessary interventions.

6. When to See a Doctor

Seek medical attention immediately if you notice:

  • Unexplained pain or weakness in the thighs, hips, or buttocks
  • Numbness, reflex loss, or foot drop
  • Rapid weight loss without clear reason

These red flags are especially concerning in newly diagnosed diabetic patients or those with fluctuating glucose levels.

7. Diagnosis


Chẩn đoán
 

Doctors will first rule out other conditions such as spinal degeneration, diabetic muscle infarction, or Meralgia paresthetica. Tests may include:

  • Blood tests for glucose control
  • Lumbar puncture for signs of inflammation
  • X-ray, CT scan, or MRI
  • Electromyography (EMG)

Early diagnosis is crucial to developing an appropriate treatment plan and preventing long-term disability.

8. Treatment of Diabetic Muscle Atrophy

There is no single definitive treatment, but most cases improve over time with proper management.
Main approaches include:

  • Blood glucose control: Maintaining stable levels through diet, exercise, and prescribed medication.
  • Pain management: Using medications such as gabapentin, pregabalin, or certain antidepressants under medical supervision.
  • Physical therapy: Preserving and restoring muscle strength.
  • Supportive therapies: Acupuncture, gentle massage, meditation, and yoga to relieve stress.

9. Lifestyle Measures for Recovery


Lối sống hỗ trợ phục hồi
 

9.1 Exercise

  • Walking, swimming, yoga
  • Avoid heavy lifting or movements that cause pain

9.2 Foot Care

  • Daily foot inspection
  • Maintain hygiene and wear proper footwear

9.3 Nutrition

  • Complex carbohydrates: brown rice, whole grains
  • Lean protein: poultry, fish, eggs, low-fat dairy
  • Healthy fats: olive oil, fish oil
  • Fiber-rich foods: fresh vegetables and fruits

Balanced nutrition helps stabilize blood glucose and supports nerve and muscle health.

10. Prevention of Diabetic Muscle Atrophy


Phòng ngừa teo cơ do đái tháo đường
 
  • Avoid smoking
  • Maintain a healthy weight
  • Keep blood glucose levels stable
  • Undergo regular health checkups
  • Use a home blood glucose meter for consistent monitoring and timely adjustments

Though rare, diabetic muscle atrophy can drastically reduce quality of life. Early recognition of symptoms, combined with strict glucose management, is the key to prevention and effective treatment.
Today, with the help of blood glucose meters and home monitoring devices, patients can take an active role in managing their condition. By adjusting diet, exercise, and medication scientifically, they can not only prevent muscle atrophy but also lower the risk of other serious diabetic complications.

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